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Diabetes drug could stop nerve damage, amputations

Soon, some diabetic patients may have fewer things to worry about — such as nerve degeneration and amputations — and more time to focus on checking their blood glucose levels.

KU researchers have developed KU-32, a drug three years in the making, which may be able to stop diabetic peripheral neuropathy, or DPN. It may also reverse some damage already done by the disorder.

The progression of the disorder is directly related to how well diabetics manage their blood glucose levels.

Rick Dobrowsky, a pharmacy and toxicology professor, has been on the research team since its earlier stages. He said it’s possible for college students to develop symptoms of DPN if they were diagnosed with juvenile diabetes.

Katie Coppaken, a senior from Overland Park has had diabetes since she was two years old. She said she checks her blood glucose level about ten times a day to avoid developing any short- or long-term complications.

“Having diabetes is a full-time job,” Coppaken said. “You don’t get a winter break. Whatever activity I’m doing, I’m always thinking about how it’s affecting my sugar levels.”

Brian Collins, a senior from Crystal Lake, Ill. who has diabetes, agreed that it’s important for diabetics to avoid complications.

“I take really good care of myself,” Collins said. “I make it a priority to take care of my blood glucose levels.”.

Dobrowsky said DPN usually affected the long nerves that go through the legs and arms. This could lead to two different types of nerve dysfunction.

DPN can cause a painful, tingling sensation, specifically in the legs.

“Imagine hitting your funny bone and having that painful sensation constantly,” Dobrowsky said.

Read the full story at the Daily Kansan.

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